Originally posted by mipmcptYou can't play the Colle without giving a slight edge to Black against the following defenses:
Such as?
Dutch Defense (1...f5) White will have trouble pushing his pawn to e4.
Any defense in which Black plays 1...g6 will probably make White's KB on d3 "bite on granite."
An early ...Bg4 by Black will limit the KN's prospects. White should transpose to a Queen's Gambit with P-c4 and target Black's queenside (especially the b7 square) which is weakened by the absense of the QB.