I used to send reminders way back in the day, but I found that people who weren't moving anyway, tended to ignore them. So I put in my profile that any "official" game (clan, tourny, etc) I won't be sending reminders - pay attention. I myself have gotten clobbered with it in games I was actually winning but couldn't move in because of whatever reason. Once, I had my computer die on me and it took a few days to get things back up and running, and guess what? I lost like 3 games to timeouts because of it. That's life. In friendly games, on the rare occasion I play them anymore, I send reminders. I also tend to check my opponents' other games to see if he's not moving in any of them or just mine. If he's silent across the board, I figure something's come up and leave it. If he's moving, but ignoring our game, he gets the axe.