Originally posted by scottishinnzAccording to the University of Utah, Mutations result when the DNA polymerase makes a mistake, which happens about once every 100,000,000 bases.
I'm just sick of going round and round with Fly whilst he brings up the same objections that I showed were wrong 5 minutes previously.
Actually, the number of mistakes that remain incorporated into the DNA is even lower than this because cells contain special DNA repair proteins that fix many of the mistakes in the DNA that are caused by mutagens. The repair proteins see which nucleotides are paired incorrectly, and then change the wrong base to the right one. So Evolution as a result of this is to unlikly
You say your sick of me, ok fine, I didnt mean to hurt you in any way, I will promise you I will stay out of your evolution debate. I will stay out of these threads.
Ben
Originally posted by flyUnityI suggest you read a little further (and by little i mean alot). For evolution to occur, variations must happen in the gametes (sex cells) so that they can be passed to the next generation.
According to the University of Utah, Mutations result when the DNA polymerase makes a mistake, which happens about once every 100,000,000 bases.
Actually, the number of mistakes that remain incorporated into the DNA is even lower than this because cells contain special DNA repair proteins that fix many of the mistakes in the DNA that are caused by mutage ...[text shortened]... l promise you I will stay out of your evolution debate. I will stay out of these threads.
Ben
Mutations in somatic cells (non-sex) are not inherited. Also the enzyme responsible for repairing "mistakes" is not completely effective. Look at cancers.
Can anyone confirm if this enzyme affects the sex-cells?
Originally posted by flyUnityI sent you a PM fly, cause I do value your input - it'd be a boring thread without you!
According to the University of Utah, Mutations result when the DNA polymerase makes a mistake, which happens about once every 100,000,000 bases.
Actually, the number of mistakes that remain incorporated into the DNA is even lower than this because cells contain special DNA repair proteins that fix many of the mistakes in the DNA that are caused by mutage ...[text shortened]... l promise you I will stay out of your evolution debate. I will stay out of these threads.
Ben
wrt you point. The human genome contains about 4,000,000,000 base pairs. Thus for every reproduction of the genome (both in somatic and germ cells) there are about 40 such mutations. What UoU fail to also say is that mutations can (and do) happen for other reasons too, such as the presence of mutagens (UV-B, radioactive substances, O-).
Mutation is rare, but DNA polymerase evolved too - it might be good now, but we can safely assume it wasn't always so good (and still isn't in, for example, bacteria). Mutation rates would be higher then, especially if solar output was higher, or ozone less prevalent (due to decreased atmospheric O2 concentrations etc).
Originally posted by ColettiIt may not be conclusive proof, but to me it seems like very strong evidence - would you agree?
All English kids love the game of marbles. From this I predict that you will find a white marble in almost every home with children in England. Now, if you find a white marble in 99% of the homes with children in England, this proves my premise?
A implies B,
and B is true,
then A is true.
That's called the fallacy of asserting the consequent.
EDIT - sorry, I read this on page 20 thinking it was the most up to date post in the thread... apparently I have 10 more pages to catch up on!
Originally posted by PawnCurryYeah, it's getting to be quite a long thread... Everytime I think it's going to end something else comes up!!!
It may not be conclusive proof, but to me it seems like very strong evidence - would you agree?
EDIT - sorry, I read this on page 20 thinking it was the most up to date post in the thread... apparently I have 10 more pages to catch up on!